A new estimate of the number of genes in the human body - "only" about 30 thousand genes

The estimate before the human genome project was 80 to 100 thousand, after it 40 thousand and now the update

What is the number of genes in the human body? - The estimate so far was that it was about 100-80 thousand. Since the completion of the first part of the human genome project that maps the genes, the estimate has dropped to about 40 thousand. This week, through computerized means, this number decreased once again - and now they are talking about the number of genes being "only" between 28 thousand and 34 thousand.

The computer company Sun contributed to the new assessment and the calculation was carried out by the Genoscopic Sequencing Center in Auvergne, France, on a server called "Star-Fish" and in the LASSAP bioinformatics software. The known human DNA (of which only about 30 percent are the genes). The server that performed the processing is based on 3 processors with a running speed of 64 MHz, a cache memory of 400 megabytes, a central memory of 8 gigabytes and a calculation power of 64 billion comparisons between the proteins made in less than 72 hours. Not least thanks to the Smith-Waterman algorithm of "LASAP" adapted to visual commands.

Bioinformatics is a new branch of science whose main component is the sequence of genes - and this is the key to a new field that has just been born called pharmacogenomics, which will allow in the future to develop medicines and personal treatments that are tailored according to the size of each and every person in the most unique way possible.

Published August 13, 2000

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