Neurodegenerative diseases

Brain scans. Illustration: depositphotos.com

Stem cell “mini-brains” reveal therapeutic direction for rare childhood disease

Researchers created brain organoids from cells from patients with a rare disease linked to the DHDDS gene, and identified impairment in lipid metabolism, glycosylation, and mitochondrial function.
Prof. Ilana Gozes. Photo: Tel Aviv University spokesperson

Women respond differently than men to drug treatment for Alzheimer's

"In women, the experimental drug delayed the deterioration significantly, protected the brain and even reduced symptoms of depression, all in accordance with the mechanism of action," says Prof. Ilana Gozes, who headed the study
Alzheimer's. Illustration: depositphotos.com

Women respond differently than men to drug treatment for Alzheimer's

Significant differences were found between the reactions of the two sexes to an innovative drug for brain degenerative diseases such as Alzheimer's disease
The beta amyloid protein. Image: depositphotos.com

Breakthrough: Freezing the progression of Alzheimer's disease by stopping amyloid fibers

Researchers from Japan have discovered a way to stop the development of amyloid β fibers, which are associated with Alzheimer's disease, using an antibody that makes it possible to stop or delay the development of the fibers. This breakthrough may help develop new treatments
Photomicrograph of a biopsy from a patient's lungs. Illustration: depositphotos.com

Towards a new generation of treatments for old age diseases

Left: cells with a mutant FUS protein that causes accumulations (in green) and leads to ALS disease. Right: the cells with the protein/chaferon (in pink) that manages to prevent the accumulations

fight degenerative diseases

The proteins and mechanisms required to fight the protein accumulations that lead to neurodegenerative diseases have been identified