degenerative diseases

Protein structure. Illustration: depositphotos.com

This is how molecular machines form tangled proteins

Weizmann Institute of Science research reveals how AAA+ family machines use an energy-efficient mechanism to thread proteins through a tiny channel, providing inspiration for the development of artificial molecular machines
Some of the students who participated in the study and the researchers. Photo by Tatiana Itkin

A study by students from Israel on the space station was published in the journal Astrobiology 

  • No comments
Right: the opening (red) of the phagophore (green) remains narrow thanks to the coordinated activity of two protein clusters. Left: The opening widened after the scientists reduced the action of the valve that is responsible for closing it

open a little mouth

This is how you maintain a balanced diet of the autophagy organs - the self-eating mechanism in our body cells that removes waste and strengthens our health
A fitness pill. Credit: The Science website via DALEE

New 'workout pill' can cause fitness benefits without exercise

  • No comments
Researchers report new compounds that appear to be able to mimic the physical drive of exercise—at least in rodent cells. This discovery may lead to a new way to treat muscular dystrophy and other medical conditions in people,
Dr. Catherine Vandorna. Photo: Nitzan Zohar, Technion spokesperson

This is how the bone marrow reacts to injuries and infections

  • No comments
Dr. Kathryn Vandorna from the Faculty of Biomedical Engineering at the Technion has developed a new method that allows the monitoring of the formation of immune blood cells in the bone marrow. For this purpose, she used tiny magnetic particles of iron oxide, which
diseases of old age. Photo: depositphotos.com

The organization of the quality control system of proteins affects the onset of neurodegenerative diseases

  • One response
Ado Kanter. Photo: Faith Baginsky.

New research on the way the brain works may help to understand neurodegenerative diseases

  • One response
Decreased mitochondrial calcium uptake in cells where the MTCH2 gene has been neutralized. The photo on the left shows a nerve cell that has not been genetically modified. The photo on the right shows a transgenic nerve cell (without MTCH2). Fluorescent sensors were inserted into the cells in order to illuminate the absorption of calcium in the mitochondria, and calcium was added to the growth medium of the cells. As you can see, the sensors illuminate significantly less in the engineered cell (the color scale ranges from blue, indicating low calcium absorption, to yellow, indicating high calcium absorption), which indicates impaired calcium absorption in the mitochondria. Source: from the article.

calcium escape from the brain

  • No comments
Neurons of a mouse embryo grown in a Petri dish. The axons, the extensions of the nerve cells, are the green extensions in the picture. Source: NIH.

A little less, a little more

  • No comments

Survival - in the brain

  • No comments
Danit Oz Levy and Amir Gelman. Standing in the back, from the right: Prof. Doron Lantz and Prof. Zebulon Elazar. rare mutations

Mistakes on the way to recycling

  • No comments
Dr. Ayelet Erez. Photo: Weizmann Institute

double track

  • No comments
elders. From Wikipedia

the barrier

  • No comments
A four-legged robot learned to change its movement style to traverse a forest and jump over obstacles

memorandum of understanding

  • No comments
Science website logo
SEARCH